Metabolism of daunorubicin by a barbiturate-sensitive aldehyde reductase from rat liver.
نویسندگان
چکیده
A barbiturate-sensitive aldehyde reductase was purified to homogeneity from rat liver and shown to metabolize the cancer-chemotherapeutic antibiotic daunorubicin. The aldehyde reductase may have important roles in the metabolism of exogeneous drugs as well as the aldehyde derivatives of the biogenic amines.
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عنوان ژورنال:
- The Biochemical journal
دوره 159 3 شماره
صفحات -
تاریخ انتشار 1976